Weeks 1-6 use 1 or 2 sprays when cigarettes normally would have been smoked or if cravings emerge.
If after a single spray cravings are not controlled within a few minutes, a second spray should be used.
If 2 sprays are required, future doses may be delivered as 2 consecutive sprays.
Most smokers will require 1-2 sprays every 30 minutes to 1 hour.
Weeks 7-9 start reducing the number of sprays per day.
By the end of week 9 subjects should be using half the average number of sprays per day that was used in Step I.
Weeks 10-12 continue reducing the number of sprays per day so that subjects are not using more than 4 sprays per day during week 12.
When subjects have reduced to 2-4 sprays per day, the spray use should be discontinued.